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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H2AFX
All Species:
44.85
Human Site:
Y40
Identified Species:
89.7
UniProt:
P16104
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16104
NP_002096.1
143
15145
Y40
R
L
L
R
K
G
H
Y
A
E
R
V
G
A
G
Chimpanzee
Pan troglodytes
XP_520760
155
16635
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Rhesus Macaque
Macaca mulatta
XP_001090149
155
16475
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Dog
Lupus familis
XP_853256
242
25674
Y139
R
L
L
R
K
G
H
Y
A
E
R
V
G
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P27661
143
15124
Y40
R
L
L
R
K
G
H
Y
A
E
R
V
G
A
G
Rat
Rattus norvegicus
P02262
130
14059
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512371
142
15010
Y40
R
L
L
R
K
G
H
Y
A
E
R
V
G
A
G
Chicken
Gallus gallus
P02263
129
13922
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Frog
Xenopus laevis
Q6GM86
139
14837
Y40
R
L
L
R
K
G
N
Y
A
H
R
V
G
A
G
Zebra Danio
Brachydanio rerio
Q7ZUY3
142
14983
Y40
R
L
L
R
K
G
N
Y
A
E
R
V
G
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P84051
124
13344
K36
R
I
H
R
L
L
R
K
G
N
Y
A
E
R
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16886
126
13432
Y40
R
F
L
R
K
G
N
Y
A
Q
R
V
G
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
79.3
58.6
N.A.
97.1
85.3
N.A.
93
85.3
84.6
87.4
N.A.
79
N.A.
N.A.
81.8
Protein Similarity:
100
81.2
81.9
59
N.A.
99.3
86.7
N.A.
94.4
86.7
90.2
90.2
N.A.
83.2
N.A.
N.A.
84.6
P-Site Identity:
100
93.3
93.3
100
N.A.
100
93.3
N.A.
100
93.3
86.6
93.3
N.A.
13.3
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
20
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
92
0
0
9
0
92
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
75
0
0
9
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
92
0
0
9
0
0
0
92
0
92
% G
% His:
0
0
9
0
0
0
34
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
92
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
84
92
0
9
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
59
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
100
0
0
100
0
0
9
0
0
0
92
0
0
9
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
92
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _